The expression of SGK, caspase-1, NLRP3, and IL-1b mRNA, as nicely as the amount of TUNEL-beneficial cells have been elevated by the aldosterone infusion in the kidneys of the salt-loaded rats. Inflammasomes are multiprotein complexes that provide as a system for caspase-one activation, which final results in TUNELpositive mobile demise and release of inflammatory cytokines
To examine renal fibrosis, we examined the expression of aSMA and collagen variety I,...