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A prediction of this speculation is that a ubiquitinated kind of dMfn exists, at the very least transiently, in wt flies, and that the abundance of this ubiquitinated type of dMfn will be significantly decreased in PINK1 and parkin mutants

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Since PINK1B9 males are sterile and the PINK1 gene resides on the X chromosome,...
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As not all strains of EAEC elicited diarrhea, the EAEC pressure 042 which induced diarrhea in the volunteer examine became the prototypical EAEC strain for the study of virulence factors and EAEC pathogenicity [7]

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The predominant facultative anaerobe resident in the human colon is the Gram-detrimental motile bacillus...
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Female C57Bl/6J mice (The Jackson Laboratory, Bar Harbor, ME) aged six? months have been immunized by intraperitoneal injection of 106 PFU MVA or MVADudg (vDG027), as indicated

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DF-1 cells were grown on glass coverslips and infected with MVA or vDG020, a...
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Since Trend-dependent amine oxidases ought to demethylate the two mono- and di-methylated substrates [two], we utilised Set7 to monomethylate H3K4 (and not the Set1 intricate which leads to trimethylation)

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Put up-translational modifications of histones regulate gene transcription both by recruiting other proteins/complexes or...
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These classspecific responses presumably crop up from differential endosomal compartmentalization and signaling, with Class A ODNs predominantly advertising IRF-7-mediated signaling from early endosomes and Course B ODNs primarily inducing late endosomal NF-kB activation [43]

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Viral decreased respiratory tract infections, particularly all those triggered by influenza viruses, keep on...
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The corresponding PrPC represented mono- or non-glycosylated PrPC in MDCK cells (Fig. 1). PrPC glycomutants and wild-sort PrPC (PrPCWT) contained the 3F4 epitope tag making it possible for discrimination of overexpressed from endogenous PrPC [32]

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One of the needs of our study was to establish the purpose of the...