7-epi-10-Deacetyltaxol
7-Epi-10-deacetyltaxol has been found in Taxus. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer potential, although research is limited.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18834896
Cas No. |
78454-17-8 |
---|---|
Purity |
≥92% |
Formula |
C45H49NO13 |
Formula Wt. |
811.87 |
Synonym |
10-Deacetyl-7-epitaxol |
Solubility |
Soluble in organic solvents. |
Appearance |
White powder |
Yu SS, Sun QW, Zhang XP, et al. Content and distribution of active components in cultivated and wild Taxus chinensis var. mairei plants. Ying Yong Sheng Tai Xue Bao. 2012 Oct;23(10):2641-7. PMID: 23359921.
Slichenmyer WJ, Von Hoff DD. New natural products in cancer chemotherapy. J Clin Pharmacol. 1990 Sep;30(9):770-88. PMID: 1980498.
Shen YC, Chen YJ, Chen CY. Taxane diterpenoids from the seeds of Chinese yew Taxus chinensis. Phytochemistry. 1999 Dec;52(8):1565-9. PMID: 10647221.