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1,4-Benzoquinone

1,4-Benzoquinone is a precursor used in the synthesis of hydroquinone and is also used as a hydrogen acceptor and oxidant. 1,4-Benzoquinone exhibits anti-inflammatory and antibiotic activities. 1,4-Benzoquinone inhibits 5-lipoxygenase and prevents leukotriene synthesis. Additionally, this compound displays antibacterial efficacy against Staphylococcus, Salmonella, and Bacillus.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18831603

Cas No.

106-51-4

Purity

≥98%

Formula

C6H4O2

Formula Wt.

108.09

Chemical Name

2,5-Cyclohexadiene-1,4-dione

IUPAC Name

cyclohexa-2,5-diene-1,4-dione

Synonym

Quinone; p-quinone; 1,4-Cyclohexadienedione

Melting Point

115.7°C

Solubility

Slightly soluble in water. Soluble in alcohol, ether or alkalis.

Appearance

Greenish powder


product targets : Complement System inhibitors

Schaible AM, Filosa R, Temml V, et al. Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. Br J Pharmacol. 2014 May;171(9):2399-412. PMID: 24467325.

Kim MH, Jo SH, Ha KS, et al. Antimicrobial activities of 1,4-benzoquinones and wheat germ extract. J Microbiol Biotechnol. 2010 Aug;20(8):1204-9. PMID: 20798583.

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