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[Arg8]-Vasotocin

Vasotocin is a peptide that acts on vasotocin receptors and exhibits anorexigenic activity in vivo. Vasotocin decreases feeding behavior, increases stress responses, and induces courtship behavior in animal models. Vasotocin is a non-mammalian vasopressin-oxytocin analog.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18829960

Purity

≥95%

Formula

C43H67N15O12S2

Formula Wt.

1050.23

IUPAC Name

1-[(4R,7S,10S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

Appearance

White to off white powder


product targets : Rhinovirus (HRV) inhibitors

Gesto M, Soengas JL, Rodríguez-Illamola A, et al. Arginine vasotocin treatment induces a stress response and exerts a potent anorexigenic effect in rainbow trout, Oncorhynchus mykiss. J Neuroendocrinol. 2013 Dec 16. [Epub ahead of print]. PMID: 24341528.

Kim JK, Kim IH, Heo JH, et al. Arginine vasotocin (AVT) triggers courtship behavior without exposure to external stimuli and modulates the olfactory response of male Hynobius leechii salamanders. Zoolog Sci. 2013 Nov;30(11):929-37. PMID: 24199858.

Hasunuma I, Toyoda F, Okada R, et al. Roles of arginine vasotocin receptors in the brain and pituitary of submammalian vertebrates. Int Rev Cell Mol Biol. 2013;304:191-225. PMID: 23809437.

MK-1775