Bergmann, R.L.; Ogra, P.L. Concluding remarks. The window of opportunity: Pre-pregnancy to 24 months of age. APTO-253 manufacturer Nestle Nutr. Workshop Ser. Pediatr. Program 2008, 61, 255?60. 82. Desai, M.; Crowther, N.J.; Lucas, A.; Hales, C.N. Organ-selective growth in the offspring of protein-restricted mothers. Br. J. Nutr. 1996, 76, 591?03. 83. Crews, F.; He, J.; Hodge, C. Adolescent cortical development: A critical period of vulnerability for addiction. Pharmacol. Biochem. Behav. 2007, 86, 189?99. 84. Gluckman, P.D.; Hanson, M.A.; Low, F.M. The role of developmental plasticity and epigenetics in human health. Birth Defects Res. C Embryo Today 2011, 93, 12?8.Nutrients 2015,85. Godfrey, K.M.; Barker, D.J. Fetal AG-490 manufacturer nutrition and adult disease. Am. J. Clin. Nutr. 2000, 71, 1344?352. 86. Symonds, M.E.; Sebert, S.P.; Hyatt, M.A.; Budge, H. Nutritional programming of the metabolic syndrome. Nat. Rev. Endocrinol. 2009, 5, 604?10. 87. Lucas, A. Programming by early nutrition in man. Ciba Found. Symp. 1991, 156, 38?0. 88. Godfrey, K.M.; Barker, D.J. Maternal nutrition in relation to fetal and placental growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 1995, 61, 15?2. 89. Langley-Evans, S.C. Developmental programming of health and disease. Proc. Nutr. Soc. 2006, 65, 97?05. 90. Gluckman, P.D.; Cutfield, W.; Hofman, P.; Hanson, M.A. The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum. Dev. 2005, 81, 51?9. 91. Edwards, L.J.; McFarlane, J.R.; Kauter, K.G.; McMillen, I.C. Impact of periconceptional nutrition on maternal and fetal leptin and fetal adiposity in singleton and twin pregnancies. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288, 39?5. 92. Edwards, L.J.; McMillen, I.C. Periconceptional nutrition programs development of the cardiovascular AG-221 web system in the fetal sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, 669?79. 93. Woods, L.L.; Weeks, D.A.; Rasch, R. Programming of adult blood pressure by maternal protein restriction: Role of nephrogenesis. Kidney Int. 2004, 65, 1339?348. 94. Zimanyi, M.A.; Denton, K.M.; Forbes, J.M.; Thallas-Bonke, V.; Thomas, M.C.; Poon, F.; Black, M.J. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal AG-490 price injury due to advanced glycation end-products. Diabetologia 2006, 49, 801?10. 95. Hoppe, C.C.; Evans, R.G.; Bertram, J.F.; Moritz, K.M. Effects of dietary protein restriction on nephron number in the mouse. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292, 1768?774. 96. Briscoe, T.A.; Rehn, A.E.; Dieni, S.; Duncan, J.R.; Wlodek, M.E.; Owens, J.A.; Rees, S.M. Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency. Am. J. Obstet. Gynecol. 2004, 191, 847?55. 97. Bassan, H.; Trejo, L.L.; Kariv, N.; Bassan, M.; Berger, E.; Fattal, A.; Gozes, I.; Harel, S. Experimental intrauterine growth retardation alters renal development. Pediatr. Nephrol. 2000, 15, 192?95. 98. Zohdi, V.; Moritz, K.M.; Bubb, K.J.; Cock, M.L.; Wreford, N.; Harding, R.; Black, M.J. Nephrogenesis and the renal renin-angiotensin system in fetal sheep: Effects of intrauterine growth restriction during late gestation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293, 1267?273. 99. Corstius, H.B.; Zimanyi, M.A.; Maka, N.; Herath, T.; Thomas, W.; van der Laarse, A.; Wreford, N.G.; Black, M.J. Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatr. Res. 2005, 57, 796.Bergmann, R.L.; Ogra, P.L. Concluding remarks. The window of opportunity: Pre-pregnancy to 24 months of age. Nestle Nutr. Workshop Ser. Pediatr. Program 2008, 61, 255?60. 82. Desai, M.; Crowther, N.J.; Lucas, A.; Hales, C.N. Organ-selective growth in the offspring of protein-restricted mothers. Br. J. Nutr. 1996, 76, 591?03. 83. Crews, F.; He, J.; Hodge, C. Adolescent cortical development: A critical period of vulnerability for addiction. Pharmacol. Biochem. Behav. 2007, 86, 189?99. 84. Gluckman, P.D.; Hanson, M.A.; Low, F.M. The role of developmental plasticity and epigenetics in human health. Birth Defects Res. C Embryo Today 2011, 93, 12?8.Nutrients 2015,85. Godfrey, K.M.; Barker, D.J. Fetal nutrition and adult disease. Am. J. Clin. Nutr. 2000, 71, 1344?352. 86. Symonds, M.E.; Sebert, S.P.; Hyatt, M.A.; Budge, H. Nutritional programming of the metabolic syndrome. Nat. Rev. Endocrinol. 2009, 5, 604?10. 87. Lucas, A. Programming by early nutrition in man. Ciba Found. Symp. 1991, 156, 38?0. 88. Godfrey, K.M.; Barker, D.J. Maternal nutrition in relation to fetal and placental growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 1995, 61, 15?2. 89. Langley-Evans, S.C. Developmental programming of health and disease. Proc. Nutr. Soc. 2006, 65, 97?05. 90. Gluckman, P.D.; Cutfield, W.; Hofman, P.; Hanson, M.A. The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum. Dev. 2005, 81, 51?9. 91. Edwards, L.J.; McFarlane, J.R.; Kauter, K.G.; McMillen, I.C. Impact of periconceptional nutrition on maternal and fetal leptin and fetal adiposity in singleton and twin pregnancies. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288, 39?5. 92. Edwards, L.J.; McMillen, I.C. Periconceptional nutrition programs development of the cardiovascular system in the fetal sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, 669?79. 93. Woods, L.L.; Weeks, D.A.; Rasch, R. Programming of adult blood pressure by maternal protein restriction: Role of nephrogenesis. Kidney Int. 2004, 65, 1339?348. 94. Zimanyi, M.A.; Denton, K.M.; Forbes, J.M.; Thallas-Bonke, V.; Thomas, M.C.; Poon, F.; Black, M.J. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products. Diabetologia 2006, 49, 801?10. 95. Hoppe, C.C.; Evans, R.G.; Bertram, J.F.; Moritz, K.M. Effects of dietary protein restriction on nephron number in the mouse. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292, 1768?774. 96. Briscoe, T.A.; Rehn, A.E.; Dieni, S.; Duncan, J.R.; Wlodek, M.E.; Owens, J.A.; Rees, S.M. Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency. Am. J. Obstet. Gynecol. 2004, 191, 847?55. 97. Bassan, H.; Trejo, L.L.; Kariv, N.; Bassan, M.; Berger, E.; Fattal, A.; Gozes, I.; Harel, S. Experimental intrauterine growth retardation alters renal development. Pediatr. Nephrol. 2000, 15, 192?95. 98. Zohdi, V.; Moritz, K.M.; Bubb, K.J.; Cock, M.L.; Wreford, N.; Harding, R.; Black, M.J. Nephrogenesis and the renal renin-angiotensin system in fetal sheep: Effects of intrauterine growth restriction during late gestation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293, 1267?273. 99. Corstius, H.B.; Zimanyi, M.A.; Maka, N.; Herath, T.; Thomas, W.; van der Laarse, A.; Wreford, N.G.; Black, M.J. Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatr. Res. 2005, 57, 796.Bergmann, R.L.; Ogra, P.L. Concluding remarks. The window of opportunity: Pre-pregnancy to 24 months of age. Nestle Nutr. Workshop Ser. Pediatr. Program 2008, 61, 255?60. 82. Desai, M.; Crowther, N.J.; Lucas, A.; Hales, C.N. Organ-selective growth in the offspring of protein-restricted mothers. Br. J. Nutr. 1996, 76, 591?03. 83. Crews, F.; He, J.; Hodge, C. Adolescent cortical development: A critical period of vulnerability for addiction. Pharmacol. Biochem. Behav. 2007, 86, 189?99. 84. Gluckman, P.D.; Hanson, M.A.; Low, F.M. The role of developmental plasticity and epigenetics in human health. Birth Defects Res. C Embryo Today 2011, 93, 12?8.Nutrients 2015,85. Godfrey, K.M.; Barker, D.J. Fetal nutrition and adult disease. Am. J. Clin. Nutr. 2000, 71, 1344?352. 86. Symonds, M.E.; Sebert, S.P.; Hyatt, M.A.; Budge, H. Nutritional programming of the metabolic syndrome. Nat. Rev. Endocrinol. 2009, 5, 604?10. 87. Lucas, A. Programming by early nutrition in man. Ciba Found. Symp. 1991, 156, 38?0. 88. Godfrey, K.M.; Barker, D.J. Maternal nutrition in relation to fetal and placental growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 1995, 61, 15?2. 89. Langley-Evans, S.C. Developmental programming of health and disease. Proc. Nutr. Soc. 2006, 65, 97?05. 90. Gluckman, P.D.; Cutfield, W.; Hofman, P.; Hanson, M.A. The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum. Dev. 2005, 81, 51?9. 91. Edwards, L.J.; McFarlane, J.R.; Kauter, K.G.; McMillen, I.C. Impact of periconceptional nutrition on maternal and fetal leptin and fetal adiposity in singleton and twin pregnancies. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288, 39?5. 92. Edwards, L.J.; McMillen, I.C. Periconceptional nutrition programs development of the cardiovascular system in the fetal sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, 669?79. 93. Woods, L.L.; Weeks, D.A.; Rasch, R. Programming of adult blood pressure by maternal protein restriction: Role of nephrogenesis. Kidney Int. 2004, 65, 1339?348. 94. Zimanyi, M.A.; Denton, K.M.; Forbes, J.M.; Thallas-Bonke, V.; Thomas, M.C.; Poon, F.; Black, M.J. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products. Diabetologia 2006, 49, 801?10. 95. Hoppe, C.C.; Evans, R.G.; Bertram, J.F.; Moritz, K.M. Effects of dietary protein restriction on nephron number in the mouse. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292, 1768?774. 96. Briscoe, T.A.; Rehn, A.E.; Dieni, S.; Duncan, J.R.; Wlodek, M.E.; Owens, J.A.; Rees, S.M. Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency. Am. J. Obstet. Gynecol. 2004, 191, 847?55. 97. Bassan, H.; Trejo, L.L.; Kariv, N.; Bassan, M.; Berger, E.; Fattal, A.; Gozes, I.; Harel, S. Experimental intrauterine growth retardation alters renal development. Pediatr. Nephrol. 2000, 15, 192?95. 98. Zohdi, V.; Moritz, K.M.; Bubb, K.J.; Cock, M.L.; Wreford, N.; Harding, R.; Black, M.J. Nephrogenesis and the renal renin-angiotensin system in fetal sheep: Effects of intrauterine growth restriction during late gestation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293, 1267?273. 99. Corstius, H.B.; Zimanyi, M.A.; Maka, N.; Herath, T.; Thomas, W.; van der Laarse, A.; Wreford, N.G.; Black, M.J. Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatr. Res. 2005, 57, 796.Bergmann, R.L.; Ogra, P.L. Concluding remarks. The window of opportunity: Pre-pregnancy to 24 months of age. Nestle Nutr. Workshop Ser. Pediatr. Program 2008, 61, 255?60. 82. Desai, M.; Crowther, N.J.; Lucas, A.; Hales, C.N. Organ-selective growth in the offspring of protein-restricted mothers. Br. J. Nutr. 1996, 76, 591?03. 83. Crews, F.; He, J.; Hodge, C. Adolescent cortical development: A critical period of vulnerability for addiction. Pharmacol. Biochem. Behav. 2007, 86, 189?99. 84. Gluckman, P.D.; Hanson, M.A.; Low, F.M. The role of developmental plasticity and epigenetics in human health. Birth Defects Res. C Embryo Today 2011, 93, 12?8.Nutrients 2015,85. Godfrey, K.M.; Barker, D.J. Fetal nutrition and adult disease. Am. J. Clin. Nutr. 2000, 71, 1344?352. 86. Symonds, M.E.; Sebert, S.P.; Hyatt, M.A.; Budge, H. Nutritional programming of the metabolic syndrome. Nat. Rev. Endocrinol. 2009, 5, 604?10. 87. Lucas, A. Programming by early nutrition in man. Ciba Found. Symp. 1991, 156, 38?0. 88. Godfrey, K.M.; Barker, D.J. Maternal nutrition in relation to fetal and placental growth. Eur. J. Obstet. Gynecol. Reprod. Biol. 1995, 61, 15?2. 89. Langley-Evans, S.C. Developmental programming of health and disease. Proc. Nutr. Soc. 2006, 65, 97?05. 90. Gluckman, P.D.; Cutfield, W.; Hofman, P.; Hanson, M.A. The fetal, neonatal, and infant environments-the long-term consequences for disease risk. Early Hum. Dev. 2005, 81, 51?9. 91. Edwards, L.J.; McFarlane, J.R.; Kauter, K.G.; McMillen, I.C. Impact of periconceptional nutrition on maternal and fetal leptin and fetal adiposity in singleton and twin pregnancies. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288, 39?5. 92. Edwards, L.J.; McMillen, I.C. Periconceptional nutrition programs development of the cardiovascular system in the fetal sheep. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, 669?79. 93. Woods, L.L.; Weeks, D.A.; Rasch, R. Programming of adult blood pressure by maternal protein restriction: Role of nephrogenesis. Kidney Int. 2004, 65, 1339?348. 94. Zimanyi, M.A.; Denton, K.M.; Forbes, J.M.; Thallas-Bonke, V.; Thomas, M.C.; Poon, F.; Black, M.J. A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products. Diabetologia 2006, 49, 801?10. 95. Hoppe, C.C.; Evans, R.G.; Bertram, J.F.; Moritz, K.M. Effects of dietary protein restriction on nephron number in the mouse. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292, 1768?774. 96. Briscoe, T.A.; Rehn, A.E.; Dieni, S.; Duncan, J.R.; Wlodek, M.E.; Owens, J.A.; Rees, S.M. Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency. Am. J. Obstet. Gynecol. 2004, 191, 847?55. 97. Bassan, H.; Trejo, L.L.; Kariv, N.; Bassan, M.; Berger, E.; Fattal, A.; Gozes, I.; Harel, S. Experimental intrauterine growth retardation alters renal development. Pediatr. Nephrol. 2000, 15, 192?95. 98. Zohdi, V.; Moritz, K.M.; Bubb, K.J.; Cock, M.L.; Wreford, N.; Harding, R.; Black, M.J. Nephrogenesis and the renal renin-angiotensin system in fetal sheep: Effects of intrauterine growth restriction during late gestation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293, 1267?273. 99. Corstius, H.B.; Zimanyi, M.A.; Maka, N.; Herath, T.; Thomas, W.; van der Laarse, A.; Wreford, N.G.; Black, M.J. Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts. Pediatr. Res. 2005, 57, 796.