Tioconazole
Tioconazole is an imidazole antifungal and antibacterial compound that damages cell membranes. Tioconazole is most active against fungi, molds, and gram positive bacteria.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18976554/
| Cas No. |
65899-73-2 |
|---|---|
| Purity |
≥98% |
| Formula |
C16H13Cl3N2OS |
| Formula Wt. |
387.71 |
| Chemical Name |
1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4- dichlorophenyl)ethyl]-1H-imidazole |
| IUPAC Name |
1-[2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole |
| Synonym |
Vagistat; Fungibacid; Trosyd; Zoniden |
| Melting Point |
168-170°C |
| Solubility |
Moderately soluble in chloroform, ethanol, methanol or ethyl acetate. |
| Appearance |
White or almost white crystalline powder |
Jones RN, Bale MJ, Hoban D, et al. In vitro antimicrobial activity of tioconazole and its concentrations in vaginal fluids following topical (vagistat-1 6.5%) application. Diagn Microbiol Infect Dis. 1993 Jul;17(1):45-51. PMID: 8359005.
Odds FC, Cheesman SL, Abbott AB. Suppression of ATP in Candida albicans by imidazole and derivative antifungal agents. Sabouraudia. 1985 Dec;23(6):415-24. PMID: 3913012.
