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Sulfadimethoxine

Sulfadimethoxine is a sulfonamide antibiotic that inhibits folic acid synthesis; it displays antibacterial efficacy in the treatment of various bacterial infections. Sulfadimethoxine is photodegraded by UV light.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18974108

Cas No.

122-11-2

Purity

≥98%

Formula

C12H14N4O4S

Formula Wt.

310.33

Chemical Name

4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzene- sulfonamide

IUPAC Name

4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide

Synonym

Agribon; Albon; Arnosulfan; Diasulfa; Madribon; Neostreptal; Sudine; Sulfabon; Ultrasulfon

Melting Point

201-203°C

Solubility

Soluble in dilute HCl, and in aqueous solutions of sodium carbonate. Ethanol (5 mg/mL).

Appearance

White Crystalline Powder

Zessel K, Mohring S, Hamscher G, et al. Biocompatibility and antibacterial activity of photolytic products of sulfonamides. Chemosphere. 2014 Apr;100:167-74. PMID: 24321335.

Mengelers MJ, van Klingeren B, van Miert AS. In vitro antimicrobial activity of sulfonamides against some porcine pathogens. Am J Vet Res. 1989 Jul;50(7):1022-8. PMID: 2774319.

HMPL-505