Pyrrolostatin
Pyrrolostatin is a pro-angiogenic free radical scavenger that improves angiogenesis in animal models. Pyrrolostatin is a lipid peroxidation inhibitor originally produced by species of Streptomyces.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18955860
Cas No. |
144314-68-1 |
---|---|
Purity |
≥98% |
Formula |
C15H21NO2 |
Formula Wt. |
247.33 |
Chemical Name |
1H-Pyrrole-2-carboxylic acid, 4-(3,7-dimethyl-2,6-octadienyl)-, (E)- |
IUPAC Name |
4-[(2E)-3,7-dimethylocta-2,6-dienyl]-1H-pyrrole-2-carboxylic acid |
Synonym |
EC 40 |
Solubility |
Soluble in methanol, ethanol, or DMSO. Insoluble in water. |
Appearance |
Dark brown powder |
Chekanov VS, Maternowski MA, Eisenstein R, et al. Angiogenesis in the latissimus dorsi muscle using different regimens of electrical stimulation and pharmaceutical support. ASAIO J. 2000 May-Jun;46(3):305-12. PMID: 10826742.
Kato S, Shindo K, Kawai H, et al. Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties. J Antibiot (Tokyo). 1993 Jun;46(6):892-9. PMID: 8344870.