Pyriproxyfen
Pyriproxyfen is a juvenile hormone mimic insecticide that is used to inhibit the development or maturation of insects such as Bemisia. In Daphnia, pyriproxyfen mimics methyl farnesoate, causing overproduction of male offspring. Pyriproxyfen also exhibits immunostimulatory activity in vivo, increasing the IgG response and resulting in increased levels of IgG2a, TNF-α, and IFN-γ.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18955707
Cas No. |
95737-68-1 |
---|---|
Purity |
≥95% |
Formula |
C20H19NO3 |
Formula Wt. |
321.37 |
Chemical Name |
2-[1-Methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine |
IUPAC Name |
2-[1-(4-phenoxyphenoxy)propan-2-yloxy]pyridine |
Synonym |
Sumilarv |
Melting Point |
45-47°C |
Solubility |
Soluble in methanol. |
Appearance |
Grey to white crystalline powder |
Sharmin T, Satho T, Irie K, et al. Pyriproxyfen enhances the immunoglobulin G immune response in mice. Microbiol Immunol. 2013 Apr;57(4):316-22. PMID: 23586635.
Ishaaya I, Kontsedalov S, Horowitz AR. Biorational insecticides: mechanism and cross-resistance. Arch Insect Biochem Physiol. 2005 Apr;58(4):192-9. PMID: 15756702.
Olmstead AW, LeBlanc GA. Insecticidal juvenile hormone analogs stimulate the production of male offspring in the crustacean Daphnia magna. Environ Health Perspect. 2003 Jun;111(7):919-24. PMID: 12782492.