Oxfendazole
Oxfendazole is a benzimidazole anti-parasitic/anti-helminthic compound that is commonly used in veterinary medicine. Oxfendazole is the sulfoxide of fenbendazole and likely inhibits microtubule polymerization. This compound exhibits efficacy against species of Fasciola, Taenia, Ascaris, Trichuris, Physocephalus, and Ascarops.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18951640
| Cas No. |
53716-50-0 |
|---|---|
| Purity |
≥98% |
| Formula |
C15H13N3O3S |
| Formula Wt. |
315.35 |
| Chemical Name |
[5-(Phenylsulfinyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester |
| IUPAC Name |
methyl N-[6-(benzenesulfinyl)-1H-benzimidazol-2-yl]carbamate |
| Synonym |
Repidose; Systamex |
| Melting Point |
253°C (dec) |
| Solubility |
Insoluble in water. Slightly soluble in acetone, chloroform, ether and methanol. |
| Appearance |
White or almost white powder |
Ortiz P, Terrones S, Cabrera M, et al. Oxfendazole flukicidal activity in pigs. Acta Trop. 2014 Aug;136:10-3. PMID: 24713198.
Mkupasi EM, Ngowi HA, Sikasunge CS, et al. Efficacy of ivermectin and oxfendazole against Taenia solium cysticercosis and other parasitoses in naturally infected pigs. Acta Trop. 2013 Oct;128(1):48-53. PMID: 23806569.
