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Nifursol

Nifursol is a nitrofuran antibiotic that is used to prevent histomoniasis. Nifursol is a livestock feed additive that exhibits antibacterial and anti-parasitic activity, especially against Histomonas.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1894885

Cas No.

16915-70-1

Purity

≥98%

Formula

C12H7N5O9

Formula Wt.

365.21

Chemical Name

3,5-Dinitrosalicylic acid (5-nitrofurfurylidene)hydrazide

IUPAC Name

2-hydroxy-3,5-dinitro-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide

Synonym

Histomon; Salfuride; Sulfuride

Melting Point

218-222°C

Appearance

Yellow Powder

Verdon E, Couedor P, Sanders P. Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD, DNSAH) by liquid chromatography coupled to electrospray tandem mass spectrometry–in-house validation in line with Commission Decision 657/2002/EC. Anal Chim Acta. 2007 Mar 14;586(1-2):336-47. PMID: 17386733.

Callait MP, Granier C, Chauve C, et al. In vitro activity of therapeutic drugs against Histomonas meleagridis (Smith, 1895). Poult Sci. 2002 Aug;81(8):1122-7. PMID: 12211302.

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