Malantide
Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18941459
| Cas No. |
86555-35-3 |
|---|---|
| Purity |
≥95% |
| Formula |
C72H124N22O21 |
| Formula Wt. |
1633.93 |
| IUPAC Name |
2-[[6-amino-2-[[2-[[1-[2-[[2-[[2-[[2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-carboxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-3-methylpentanoic acid |
| Appearance |
White to off white powder |
de Boer AR, Letzel T, Lingeman H, et al. Systematic development of an enzymatic phosphorylation assay compatible with mass spectrometric detection. Anal Bioanal Chem. 2005 Feb;381(3):647-55. PMID: 15703914.
Murray KJ, England PJ, Lynham JA, et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J. 1990 May 1;267(3):703-8. PMID: 2160235.
