LH846
LH846 is an inhibitor of casein kinase 1δ (CK1δ) that also displays activity against CK1α and CK1ε. In research models, this compound lengthens the circadian period.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18940262
| Cas No. |
639052-78-1 |
|---|---|
| Formula |
C16H13ClN2OS |
| Formula Wt. |
316.80 |
| IUPAC Name |
N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
Lee JW, Hirota T, Peters EC, et al. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. PMID: 21954091.
