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Elvitegravir

Elvitegravir is an antiviral compound that inhibits integrase activity. This compound is clinically used to treat HIV infection.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1890122

Cas No.

697761-98-1

Purity

≥98%

Formula

C23H23ClFNO5

Formula Wt.

447.88

IUPAC Name

6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxoquinoline-3-carboxylic acid

Appearance

White to off white powder

Reviriego C. Elvitegravir for the treatment of HIV infection. Drugs Today (Barc). 2014 Mar;50(3):209-17. PMID: 24696866.

Shimura K, Kodama E, Sakagami Y, et al. Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137). J Virol. 2008 Jan;82(2):764-74. PMID: 17977962.

Nazartinib