Dacarbazine
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1885595
| Cas No. |
4342-03-4 |
|---|---|
| Purity |
≥98% |
| Formula |
C6H10N6O |
| Formula Wt. |
182.18 |
| Chemical Name |
5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4- carboxamide |
| IUPAC Name |
(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
| Synonym |
Dacatic; DTIC-Dome; Deticene |
| Melting Point |
205°C |
| Solubility |
Slightly soluble in water and alcohol. |
| Appearance |
Light pink powder |
Gallamini A, Di Raimondo F, La Nasa G, et al. Standard therapies versus novel therapies in Hodgkin lymphoma. Immunol Lett. 2013 Sep-Oct;155(1-2):56-9. PMID: 24140162.
Koprowska K, Czyż M. Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities. Postepy Hig Med Dosw (Online). 2011 Nov 23;65:734-51. PMID: 22173438.
