D,L-Aminoglutethimide
D,L-Aminogluthethimide is an inhibitor of aromatase and adrenal steroid synthesis that exhibits immunosuppressive and anticancer chemotherapeutic activities. This compound is used to treat breast cancer and Cushing’s disease.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1885569
| Cas No. |
125-84-8 |
|---|---|
| Purity |
≥98% |
| Formula |
C13H16N2O2 |
| Formula Wt. |
232.28 |
| Chemical Name |
3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione |
| IUPAC Name |
3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
| Synonym |
Aminoglutethimide; Cytadren; Elipten; Orimeten |
| Melting Point |
149-150°C |
| Solubility |
Soluble in organic solvents except ethyl acetate and ethanol. Insoluble in water. |
| Appearance |
White Crystalline Powder |
Pozza C, Graziadio C, Giannetta E, et al. Management Strategies for Aggressive Cushings Syndrome: From Macroadenomas to Ectopics. J Oncol. 2012;2012:685213. PMID: 22934113.
Dubrovsky B. Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system: potential therapeutic benefits. Med Hypotheses. 1997 Jul;49(1):51-5. PMID: 9247908.
