D-Ala-D-Ala
D-Ala-D-Ala is a peptidoglycan cell wall peptide epitope to which antibacterial compounds such as vancomycin bind.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18855146
| Cas No. |
923-16-0 |
|---|---|
| Purity |
≥98% |
| Formula |
C6H12N2O3 |
| Formula Wt. |
160.17 |
| IUPAC Name |
2-[[(2R)-2-aminopropanoyl]amino]propanoic acid |
| Appearance |
White to off white powder |
Kwun MJ, Novotna G, Hesketh AR, et al. In vivo studies suggest that induction of VanS-dependent vancomycin resistance requires binding of the drug to D-Ala-D-Ala termini in the peptidoglycan cell wall. Antimicrob Agents Chemother. 2013 Sep;57(9):4470-80. PMID: 23836175.
