CUDC-907
CUDC-907 is an inhibitor of PI3K and class I and II histone deacetylases (HDACs). This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in a variety of cancer models.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18853979
| Cas No. |
1339928-25-4 |
|---|---|
| Purity |
≥98% |
| Formula |
C23H24N8O4S |
| Formula Wt. |
508.55 |
| IUPAC Name |
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide |
| Appearance |
White Crystal Powder |
Qian C, Lai CJ, Bao R, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13. PMID: 22693356.
