Chymostatin
Chymostatin is an inhibitor of proteases such as chymase that is used in research models.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18851850
| Cas No. |
9076-44-2 |
|---|---|
| Purity |
≥98% |
| Formula |
C20H16N2O4 |
| Formula Wt. |
1809.1 |
| IUPAC Name |
(2S)-2-[[(1S)-1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-phenylpropan-2-yl]amino]pentan-2-yl]amino]-2-oxoethyl]carbamoylamino]-3-phenylpropanoic acid |
| Synonym |
N-(Nα-Carbonyl-Cpd-X-Phe-al)-Phe |
| Melting Point |
276-278°C |
| Solubility |
Soluble in DMSO. |
| Appearance |
White Powder |
Paliwal D, Panda SK, Kapur N, et al. Hepatitis E virus (HEV) protease: a chymotrypsin-like enzyme that processes both non-structural (pORF1) and capsid (pORF2) protein. J Gen Virol. 2014 Aug;95(Pt 8):1689-700. PMID: 24795447.
Wang T, Han SX, Zhang SF, et al. Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters. Respir Res. 2010 Mar 31;11:36. PMID: 20356378.
