C59
C59 is a PORCN inhibitor that exhibits anticancer chemotherapeutic activity, inhibiting the progression of mammary tumors in vivo by downregulating Wnt signaling.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1884598
| Cas No. |
1243243-89-1 |
|---|---|
| Purity |
≥98% |
| Formula |
C25H21N3O |
| Formula Wt. |
379.45 |
| IUPAC Name |
2-[4-(2-methylpyridin-4-yl)phenyl]-N-(4-pyridin-3-ylphenyl)acetamide |
| Synonym |
Wnt-C59 |
| Appearance |
White to off white powder |
Proffitt KD, Madan B, Ke Z, et al. Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. Cancer Res. 2013 Jan 15;73(2):502-7. PMID: 23188502.
