Anti-TNFSF7 / CD27L / CD70 Reference Antibody (Vorsetuzumab mafodotin)

Product Name :
Anti-TNFSF7 / CD27L / CD70 Reference Antibody (Vorsetuzumab mafodotin)

synonym :

productDescription :
Vorsetuzumab mafodotin is a humanized anti-CD70 monoclonal antibody attached to a potent, synthetic drug payload, monomethyl auristatin F (MMAF) utilizing Seattle Genetics’ proprietary antibody-drug conjugate (ADC) technology. CD70 is expressed on a variety of solid tumors, including renal cell carcinoma, pancreatic, ovarian and lung cancer, as well as multiple myeloma and several types of non-Hodgkin lymphoma.

molecularWeight :
146.1 kDa

endotoxin :
<0.001 EU/ug

purity :
>95% as determined by SEC-HPLC.

formulation :
100 mM Pro-Ac 20mM Arg pH 5.0

storage :
-80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles.

reactivity :
Human

concentration :
5.90 mg/mL

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Ubiquitin Ligase- ubiquitin-ligase

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