Product Name :
Tiaprost
Description:
Tiaprost is a prostaglandin F2α (PGF2α) analogue.
CAS:
71116-82-0
Molecular Weight:
396.50
Formula:
C20H28O6S
Chemical Name:
(5E)-7-3,5-dihydroxy-2-[(1E)-3-hydroxy-4-(thiophen-3-yloxy)but-1-en-1-yl]cyclopentylhept-5-enoic acid
Smiles :
OC(=O)CCC/C=C/CC1C(/C=C/C(O)COC2=CSC=C2)C(O)CC1O
InChiKey:
FYBFDIIAPRHIQS-SYJKBYRUSA-N
InChi :
InChI=1S/C20H28O6S/c21-14(12-26-15-9-10-27-13-15)7-8-17-16(18(22)11-19(17)23)5-3-1-2-4-6-20(24)25/h1,3,7-10,13-14,16-19,21-23H,2,4-6,11-12H2,(H,24,25)/b3-1+,8-7+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tiaprost is a prostaglandin F2α (PGF2α) analogue.|Product information|CAS Number: 71116-82-0|Molecular Weight: 396.50|Formula: C20H28O6S|Chemical Name: (5E)-7-3,5-dihydroxy-2-[(1E)-3-hydroxy-4-(thiophen-3-yloxy)but-1-en-1-yl]cyclopentylhept-5-enoic acid|Smiles: OC(=O)CCC/C=C/CC1C(/C=C/C(O)COC2=CSC=C2)C(O)CC1O|InChiKey: FYBFDIIAPRHIQS-SYJKBYRUSA-N|InChi: InChI=1S/C20H28O6S/c21-14(12-26-15-9-10-27-13-15)7-8-17-16(18(22)11-19(17)23)5-3-1-2-4-6-20(24)25/h1,3,7-10,13-14,16-19,21-23H,2,4-6,11-12H2,(H,24,25)/b3-1+,8-7+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Vortioxetine Purity |Shelf Life: ≥12 months if stored properly.Ociperlimab MedChemExpress |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33016237 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Plasma progesterone levels decrease sharply within 12 hours after the initial treatment with Tiaprost and within 24 hours reach levels at about 3.18 nM (1 ng/mL). Over the following days, progesterone levels remain either slightly above (cows 1, 3, 5 and 6) or below (cow 2) 3.18 nM. In cow 4, levels remain for 17 days above 3.18 nM and drop below this level thereafter. At term, all cows show the lowest recorded progesterone levels (1 to 2 nM). Repeated luteolytic treatments with Tiaprost (cows 1 and 2) or estradio1 benzoate (cow 3) has no further influence on individual progesterone levels. Treatment with progesterone-releasing intravaginal device (PRID) does not significantly elevate progesterone plasma levels. Total estrogens in plasma remained in general unchanged.|Products are for research use only. Not for human use.|