Product Name :
Evans Blue
Description:
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). IC50 value: 220/150 nMTarget: L-glutamate uptake receptorEvans blue is a biological dye, for detection of cell survival. Evans Blue can not penetrate healthy cell membrane, but can penetrate into death cell. Binds with high affinity to serum albumin.
CAS:
314-13-6
Molecular Weight:
960.81
Formula:
C34H24N6Na4O14S4
Chemical Name:
tetrasodium (6Z)-4-amino-6-[2-(4′-2-[(2Z)-8-amino-1-oxo-5,7-disulfonato-1,2-dihydronaphthalen-2-ylidene]hydrazin-1-yl-3,3′-dimethyl-[1,1′-biphenyl]-4-yl)hydrazin-1-ylidene]-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate
Smiles :
[Na+].[Na+].[Na+].[Na+].CC1C=C(C=CC=1N/N=C1/C=CC2=C(C/1=O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O)C1C=C(C)C(=CC=1)N/N=C1/C=CC2=C(C/1=O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O
InChiKey:
KBNIFDASRCWYGC-KJPFXMIPSA-J
InChi :
InChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,37-38H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-23-,40-24-;;;;
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Glipizide Biological Activity
Shelf Life:
≥12 months if stored properly.Belimumab Apoptosis
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).PMID:33252507 Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). IC50 value: 220/150 nMTarget: L-glutamate uptake receptorEvans blue is a biological dye, for detection of cell survival. Evans Blue can not penetrate healthy cell membrane, but can penetrate into death cell. Binds with high affinity to serum albumin.|Product information|CAS Number: 314-13-6|Molecular Weight: 960.81|Formula: C34H24N6Na4O14S4|Chemical Name: tetrasodium (6Z)-4-amino-6-[2-(4′-2-[(2Z)-8-amino-1-oxo-5,7-disulfonato-1,2-dihydronaphthalen-2-ylidene]hydrazin-1-yl-3,3′-dimethyl-[1,1′-biphenyl]-4-yl)hydrazin-1-ylidene]-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate|Smiles: [Na+].[Na+].[Na+].[Na+].CC1C=C(C=CC=1N/N=C1/C=CC2=C(C/1=O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O)C1C=C(C)C(=CC=1)N/N=C1/C=CC2=C(C/1=O)C(N)=C(C=C2S([O-])(=O)=O)S([O-])(=O)=O|InChiKey: KBNIFDASRCWYGC-KJPFXMIPSA-J|InChi: InChI=1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,37-38H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-23-,40-24-;;;;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 25 mg/mL (26.02 mM). H2O : 33.33 mg/mL (34.69 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
