Product Name :
QX-314 chloride
Description:
QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker.
CAS:
5369-03-9
Molecular Weight:
298.85
Formula:
C16H27ClN2O
Chemical Name:
[(2,6-dimethylphenyl)carbamoyl]methyltriethylazanium chloride
Smiles :
[Cl-].CC1C=CC=C(C)C=1NC(=O)C[N+](CC)(CC)CC
InChiKey:
LLPPOMUAOGMYQI-UHFFFAOYSA-N
InChi :
InChI=1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker.|Product information|CAS Number: 5369-03-9|Molecular Weight: 298.85|Formula: C16H27ClN2O|Chemical Name: [(2,6-dimethylphenyl)carbamoyl]methyltriethylazanium chloride|Smiles: [Cl-].CC1C=CC=C(C)C=1NC(=O)C[N+](CC)(CC)CC|InChiKey: LLPPOMUAOGMYQI-UHFFFAOYSA-N|InChi: InChI=1S/C16H26N2O.Mouse IgG1 kappa, Isotype Control Description ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 14.Sitagliptin phosphate custom synthesis 29 mg/mL (47.PMID:32946296 82 mM; Need ultrasonic). H2O : 50 mg/mL (167.31 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|QX-314 chloride exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels (TRPV1) in vitro. QX-314 chloride (1–60 mM) directly activates TRPV1 in a concentration-dependent manner. QX-314 chloride (10 mM) inhibits calcium currents in hippocampal CA1 pyramidal neurons intracellular, and the low-threshold (T-type) Ca2+ currents are on average Products are for research use only. Not for human use.|
