Product Name :
Daun02
Description:
Daun02 is a Cell viability inhibitor and DNA synthisis inhibitor with IC50 values of 1.5 μM, 3.5 μM and 0.5 μM, respectively. Daun02 is also a anthracycline prodrug. Daun02 is a good substrate for beta-gal. Daun02 may be useful as a prodrug-activating enzyme in suicide gene therapy and has the potential to increase the selective toxicity of conventional antitumor agents.
CAS:
290304-24-4
Molecular Weight:
884.79
Formula:
C41H44N2O20
Chemical Name:
(3-nitro-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl)methyl N-[(2S,3S,4S,6R)-6-[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy-3-hydroxy-2-methyloxan-4-yl]carbamate
Smiles :
CC(=O)[C@]1(O)CC2=C([C@H](C1)O[C@H]1C[C@H](NC(=O)OCC3=CC(=C(C=C3)O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[N+]([O-])=O)[C@H](O)[C@H](C)O1)C(O)=C1C(C(=O)C3=CC=CC(OC)=C3C1=O)=C2O
InChiKey:
BOIXMGNMIWJAEW-LCTCPDETSA-N
InChi :
InChI=1S/C41H44N2O20/c1-15-31(46)20(42-40(54)59-14-17-7-8-22(21(9-17)43(56)57)62-39-38(53)37(52)34(49)25(13-44)63-39)10-26(60-15)61-24-12-41(55,16(2)45)11-19-28(24)36(51)30-29(33(19)48)32(47)18-5-4-6-23(58-3)27(18)35(30)50/h4-9,15,20,24-26,31,34,37-39,44,46,48-49,51-53,55H,10-14H2,1-3H3,(H,42,54)/t15-,20-,24-,25+,26-,31+,34-,37-,38+,39+,41-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Daun02 is a Cell viability inhibitor and DNA synthisis inhibitor with IC50 values of 1.5 μM, 3.5 μM and 0.5 μM, respectively. Daun02 is also a anthracycline prodrug. Daun02 is a good substrate for beta-gal. Daun02 may be useful as a prodrug-activating enzyme in suicide gene therapy and has the potential to increase the selective toxicity of conventional antitumor agents.|Product information|CAS Number: 290304-24-4|Molecular Weight: 884.79|Formula: C41H44N2O20|Synonym:|Daun 02|Daun-02|Chemical Name: (3-nitro-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl)methyl N-[(2S,3S,4S,6R)-6-[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy-3-hydroxy-2-methyloxan-4-yl]carbamate|Smiles: CC(=O)[C@]1(O)CC2=C([C@H](C1)O[C@H]1C[C@H](NC(=O)OCC3=CC(=C(C=C3)O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[N+]([O-])=O)[C@H](O)[C@H](C)O1)C(O)=C1C(C(=O)C3=CC=CC(OC)=C3C1=O)=C2O|InChiKey: BOIXMGNMIWJAEW-LCTCPDETSA-N|InChi: InChI=1S/C41H44N2O20/c1-15-31(46)20(42-40(54)59-14-17-7-8-22(21(9-17)43(56)57)62-39-38(53)37(52)34(49)25(13-44)63-39)10-26(60-15)61-24-12-41(55,16(2)45)11-19-28(24)36(51)30-29(33(19)48)32(47)18-5-4-6-23(58-3)27(18)35(30)50/h4-9,15,20,24-26,31,34,37-39,44,46,48-49,51-53,55H,10-14H2,1-3H3,(H,42,54)/t15-,20-,24-,25+,26-,31+,34-,37-,38+,39+,41-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.SCF Protein, Mouse medchemexpress |Shelf Life: ≥12 months if stored properly.SARS-CoV-2 S1 Protein (HEK293) Data Sheet |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33141469 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
