Anti-CD79b Reference Antibody (Polatuzumab vedotin-piiq) | Ubiquitin Ligase-ubiquitin-ligase.com

Product Name :
Anti-CD79b Reference Antibody (Polatuzumab vedotin-piiq)

synonym :

productDescription :
Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.

molecularWeight :
150.53 kDa

endotoxin :
<0.001 EU/ug

purity :
>95% as determined by SDS-PAGE.

formulation :
1×PBS 6.0

storage :
-80°C for 2 years under sterile conditions； -20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles.

reactivity :
Human[US9845355B2]

concentration :
12.5 mg/mL

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Ubiquitin Ligase- ubiquitin-ligase

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