were not important, likely due to the modest sample size, the low recurrence price, as well as the quick follow-up period right after anticoagulation suspension.Benefits: A total of 80 patients had been enrolled in this study. There were 48 patients (60 ) with high-risk mortality PE and 32 individuals (40 ) classified as intermediate danger mortality PE. Seven sufferers (8.75 ) had died in the time of hospital discharge and all of those have been classified inside the high-risk mortality group. All 73 patients who were alive at discharge have been alive immediately after three months adhere to up. There have been 1 patient (1.25 ) of key bleeding and 7 (eight.75 ) of minor bleeding. Conclusions: Accelerated regimen with 0.6mg per kilogram of body weight more than 15 minutes of alteplase was initiallyeffective and protected on Vietnamese patients with acute CDK4 Inhibitor Species Pulmonary embolism just after three months adhere to up. Table 1: The characteristic of dead case Patient Sex Age LOS Cardiac arrest as a result of PE Detail No 1. Female 54 8 Yes Comatose with multiorgan failure following cardiac arrest No two. Female 94 18 No Initially improved but develiped ventilator associated pneumonia and septic shock at day 3. No three. Male 69 1 No Hemodynamic had been not improved. Individuals delegate did not agree to thrombectomy (patient had pre-existing colon cancer). No 4. Female 75 2 Yes Comatose immediately after cardiac arrest in spite of returning to spontaneous circulation No 5. Male 59 1 Yes Refractory shock No six. Female 63 1 Yes Cardiac arrest soon after diagnosis with no ROSC No 7. Male 74 1 No Lung cancer was identified 1 day right after working with alteplase. Hemodynamic had been not improved and therapy withdrawnPB1278|The Accelerated Regimen of Low Dose Recombinant Tissue-type Plasminogen for the Remedy of Acute Pulmonary Embolism: A Case Series from Vietnam B.H. Hoang1; G.P. Do2; D.L. Le3; T.H.T. Bui4; N.T. Bui5; M.Q. Nguyen3; D.A. Nguyen4; M.M Dinh6; L.H. NguyenTable two: In-hospital adverse events High- danger mortality PE group n = 48 Intermediate-high risk PE group n = 32 Total N = 80 Probability value Age 60.six 18.84 63.1 18.71 61.six 18.71 0.42 (sign test) Length of stay 9.7 6.76 7.9 4.91 8.9 5.99 0.25 (sign test) Inhospital bleeding complications Significant intracranial bleeding 0 0 Big bleeding or needing a blood transfusion 0 1 (blood loss on account of menstrual bleeding) Minor bleeding (bleeding as a result of urethral/stomach catheter placement, bleeding tooth) 2 (four.two ) 5 (15.six ) 0.086 (Fisher’s precise test) Furthermore, there were 2/80 (2.5 ) individuals who developed chronic thromboembolic pulmonary hypertension at three months follow up.Hanoi Healthcare University Hospital Hanoi DP Inhibitor site Medical University, Hanoi,Vietnam; 2Hanoi Health-related University Hospital, Hanoi, Vietnam; 3Thu Duc District Hospital, Ho Chi Minh City, Vietnam; 4Hanoi Medical University, Hanoi, Vietnam; 5Thu Duc District Hospital – Pham Ngoc Thach Healthcare College, Ho Chi Minh City, Vietnam; 6Royal Prince Alfred Hospital- The University of Sydney, Sydney Medical School, Sydney, AustraliaPB1279|Efficacy and Security Comparison of DOACs versus Background: Pulmonary reperfusion in acute pulmonary embolism (PE) by utilizing a fixed complete dose regimen of one hundred mg of recombinant tissue-type plasminogen activator (rt-PA) more than two hours or an accelerated low-dose rt-PAregimen has not merely been controversial in Vietnam. Aims: To describe the outcomes of an accelerated low-dose rt-PA regimen for the therapy of higher to intermediate mortality risk PE in Vietnamese individuals. Strategies: This was a case series study, the PE sufferers of higher to intermediate