Toltrazuril
Toltrazuril is an anti-parasitic compound that inhibits mitochondrial respiration and pyrimidine synthesis. Toltrazuril treats coccidiosis in livestock and is also active against Toxoplasma and other microbes.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18977120
| Cas No. |
69004-03-1 |
|---|---|
| Purity |
≥98% |
| Formula |
C18H14F3N3O4S |
| Formula Wt. |
425.38 |
| Chemical Name |
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione,1-methyl-3-(3- methyl-4-(4-((trifluoromethyl)thio)phenoxy)phenyl)- |
| IUPAC Name |
1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfanyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione |
| Synonym |
Baycox; Bay Vi 9142 |
| Melting Point |
194°C |
| Solubility |
Soluble in water. |
| Appearance |
White Crystal Powder |
Iqbal A, Tariq KA, Wazir VS, et al. Antiparasitic efficacy of Artemisia absinthium, toltrazuril and amprolium against intestinal coccidiosis in goats. J Parasit Dis. 2013 Apr;37(1):88-93. PMID: 24431547.
Kul O, Yildiz K, Ocal N, et al. In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: a novel strategy for prevention of human exposure to meat-borne toxoplasmosis. Res Vet Sci. 2013 Apr;94(2):269-76. PMID: 22954788.
Harder A, Haberkorn A. Possible mode of action of toltrazuril: studies on two Eimeria species and mammalian and Ascaris suum enzymes. Parasitol Res. 1989;76(1):8-12. PMID: 2560189.
