Thymidine
Thymidine (T) is a pyrimidine nucleoside base that pairs with adenosine (A) in double-stranded DNA. Thymidine is sometimes used to synchronize cells in the S phase of mitosis.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18976268
Cas No. |
50-89-5 |
---|---|
Purity |
≥98% |
Formula |
C10H14N2O5 |
Formula Wt. |
242.23 |
IUPAC Name |
1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
Synonym |
Deoxythymidine, deoxyribosylthymine, thymine deoxyriboside |
Appearance |
White to off white powder |
Wang X, Pan L, Mao N, et al. Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines. Cancer Cell Int. 2013 Jul 30;13(1):77. PMID: 23899403.
Banfalvi G. Synchronization of mammalian cells and nuclei by centrifugal elutriation. Methods Mol Biol. 2011;761:25-45. PMID: 21755439.
Langridge R, Marvin DA, Seeds WE, et al. The molecular configuration of deoxyribonucleic acid *: II. Molecular models and their fourier transforms. J Mol Bio. Apr 1960;2(1):38-62.
Doty, P. The physical chemistry of deoxyribonucleic acids. J Cell and Comp Phys. May 1957;49(S1);27-57.