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Thymidine

Thymidine (T) is a pyrimidine nucleoside base that pairs with adenosine (A) in double-stranded DNA. Thymidine is sometimes used to synchronize cells in the S phase of mitosis.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18976268

Cas No.

50-89-5

Purity

≥98%

Formula

C10H14N2O5

Formula Wt.

242.23

IUPAC Name

1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Synonym

Deoxythymidine, deoxyribosylthymine, thymine deoxyriboside

Appearance

White to off white powder

Wang X, Pan L, Mao N, et al. Cell-cycle synchronization reverses Taxol resistance of human ovarian cancer cell lines. Cancer Cell Int. 2013 Jul 30;13(1):77. PMID: 23899403.

Banfalvi G. Synchronization of mammalian cells and nuclei by centrifugal elutriation. Methods Mol Biol. 2011;761:25-45. PMID: 21755439.

Langridge R, Marvin DA, Seeds WE, et al. The molecular configuration of deoxyribonucleic acid *: II. Molecular models and their fourier transforms. J Mol Bio. Apr 1960;2(1):38-62.

Doty, P. The physical chemistry of deoxyribonucleic acids. J Cell and Comp Phys. May 1957;49(S1);27-57.

BKM 121