Tenatoprazole
Tenatoprazole is an inhibitor of the H+/K+ ATPase that prevents gastric acid secretion, exhibiting antacid activity.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18975264
| Cas No. |
113712-98-4 |
|---|---|
| Purity |
≥98% |
| Formula |
C16H18N4O3S |
| Formula Wt. |
346.41 |
| Chemical Name |
5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-pyridinyl)methyl]sulphinyl}-1H-imidazo[4,5-b]pyridine |
| IUPAC Name |
5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine |
| Synonym |
Protop; Ulsacare |
| Melting Point |
173-175°C |
| Solubility |
Soluble in dichlormethane. |
| Appearance |
White or off-white powder |
Li H, Meng L, Liu F, et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID: 23205582.
Shin JM, Homerin M, Domagala F, et al. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. PMID: 16405921.
