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Senegenin

Senegenin is found in Polygata tennifolia; it increases NR2B NMDA receptor subunit expression in the hippocampus, showing benefit as a potential treatment for cognitive dysfunction.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18971914

Cas No.

2469-34-3

Purity

≥98%

Formula

C30H45ClO6

Formula Wt.

537.13

IUPAC Name

13-(chloromethyl)-2,3-dihydroxy-4,6a,11,11,14b-pentamethyl-2,3,4a,5,6,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picene-4,8a-dicarboxylic acid

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Xie W, Yang Y, Gu X, et al. Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats. PLoS One. 2012;7(9):e45575. PMID: 23029109.

ONC-202