Secnidazole
Secnidazole is a nitroimidazole antifungal that also exhibits antibacterial and anti-parasitic activities. Secnidazole inhibits nucleic acid synthesis in microbial cells.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18971535
| Cas No. |
3366-95-8 |
|---|---|
| Purity |
≥98% |
| Formula |
C7H11N3O3 |
| Formula Wt. |
185.18 |
| Chemical Name |
α,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol |
| IUPAC Name |
1-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol |
| Synonym |
Flagentyl |
| Melting Point |
76°C |
| Solubility |
Soluble in water. |
| Appearance |
Creamy White Crystalline Powder |
Almirall P, Escobedo AA, Ayala I, et al. Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trial. J Parasitol Res. 2011;2011:636857. PMID: 22174992.
De Backer E, Dubreuil L, Brauman M, et al. In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis. Clin Microbiol Infect. 2010 May;16(5):470-2. PMID: 19548924.
