S-Sulforaphene
S-Sulforaphene is an isothiocyanate found in plants in the Brassicaceae family, such as radishes. This compound exhibits herbicidal and anticancer activities. S-Sulforaphene inhibits proliferation of colon adenocarcinoma cells and suppresses growth of velvetleaf seedlings. Like other isothiocyanates, S-sulforaphene may also exhibit chemopreventive benefit and induce phase II enzymes.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18971242
| Cas No. |
592-95-0 |
|---|---|
| Purity |
≥98% |
| Formula |
C6H9NOS2 |
| Formula Wt. |
175.27 |
| Chemical Name |
(-)4-Isothiocyanato-4R-(methylsulfinyl)-1-butene |
| IUPAC Name |
(E)-4-isothiocyanato-1-methylsulfinylbut-1-ene |
| Synonym |
Raphanin; Sativin |
| Solubility |
Soluble in water, methanol, DMSO, or chloroform. |
| Appearance |
Slight yellow oil |
Kim KH, Moon E, Kim SY, et al. 4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. J Ethnopharmacol. 2014;151(1):503-8. PMID: 24231071.
Beevi SS, Mangamoori LN, Subathra M, et al. Hexane extract of Raphanus sativus L. roots inhibits cell proliferation and induces apoptosis in human cancer cells by modulating genes related to apoptotic pathway. Plant Foods Hum Nutr. 2010 Sep;65(3):200-9. PMID: 20652750.
Brinker AM, Spencer GF. Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84. PMID: 24248575.
