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SIVmac239-2

SIVmac239 is a highly pathogenic strain of simian immunodeficiency virus; it is a primate analog of HIV that is designed to study the effects of the immunodeficiency virus in Rhesus macaques. Like HIV, SIVmac239 primarily infects lymphoid and myeloid cells. This sequence is a peptide fragment.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18973270

Purity

≥95%

Formula

C70H123N19O25

Formula Wt.

1630.87

Münch J, Sauermann U, Yolamanova M, et al. Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus. Retrovirology. 2013 Dec 5;10:148. PMID: 24308721.

Xu Y, Weatherall C, Bailey M, et al. Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques. J Virol. 2013 Apr;87(7):3760-73. PMID: 23325697.

Luciw PA, Shaw KE, Unger RE, et al. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res Hum Retroviruses. 1992 Mar;8(3):395-402. PMID: 1571198.

Naidu YM, Kestler HW 3rd, Li Y, et al. Characterization of infectious molecular clones of simian immunodeficiency virus (SIVmac) and human immunodeficiency virus type 2: persistent infection of rhesus monkeys with molecularly cloned SIVmac. J Virol. 1988 Dec;62(12):4691-6. PMID: 2846880.

LBH590