Racecadotril
Racecadotril is an inhibitor of enkephalinase that prevents degradation of endogenous opioids and decreases secretion of water and electrolytes in the intestines. Racecadotril exhibits anti-secretory and antidiarrheal activities and is clinically used to treat diarrhea.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18957219
| Cas No. |
81110-73-8 |
|---|---|
| Purity |
≥98% |
| Formula |
C21H23NO4S |
| Formula Wt. |
385.48 |
| Chemical Name |
N-[2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]- glycine phenylmethyl ester |
| IUPAC Name |
benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate |
| Synonym |
Acetorphan; Hidrasec; Tiorfan |
| Melting Point |
89°C |
| Solubility |
Soluble in methanol, ethanol (75 mg/ml), DMSO (45 mg/ml), or chloroform. |
| Appearance |
White Crystalline Powder |
Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35; discussion 836-7. PMID: 10804038.
Lecomte JM. An overview of clinical studies with racecadotril in adults. Int J Antimicrob Agents. 2000 Feb;14(1):81-7. PMID: 10717506.
