RGD-4C
RGD-4C is a cell-adhesive peptide that binds αvβ3 and αvβ5 integrins; these integrins are overexpressed in many cancers and growing vessels, so RGD-4C is often attached to viral treatments to better deliver or target the treatment to cancerous tissues. RGD-4C exhibits anticancer chemotherapeutic and anti-angiogenic benefits in models of various cancers, including non-small cell lung cancer (NSCLC), melanoma, and glioma.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18958294
Purity |
≥95% |
---|---|
Formula |
C42H60N14O16S4 |
Formula Wt. |
1145.29 |
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