RF-NH2
RF-NH2 is a member of the RF-amide peptide family that signals through GPCRs and acid-sensing ion channels. RF-NH2 may display pro-nociceptive and opioid-modulating characteristics.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18958203
| Cas No. |
34388-59-5 |
|---|---|
| Purity |
≥95% |
| Formula |
C15H24N6O2 |
| Formula Wt. |
320.4 |
| IUPAC Name |
N5-(Diaminomethylene)-L-ornithyl-L-phenylalaninamide |
| Synonym |
RF amide peptide |
Bass C, Katanski C, Maynard B, et al. Conserved residues in RF-NH2 receptor models identify predicted contact sites in ligand-receptor binding. Peptides. 2013 Jun 26. pii: S0196-9781(13)00226-X. [Epub ahead of print]. PMID: 23811075.
Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 2006 May;27(5):943-52. PMID: 16443306.
Schiebe M, Orchard I, Watts R, et al. Characterization and partial purification of different factors with contraction-potentiating activities from neurohaemal organs of the locust. J Comp Neurol. 1990 Jan 8;291(2):305-12. PMID: 2298936.
