RFDS
RFDS is often used as a negative control for RGD peptide activity. RFDS exhibits immunomodulatory activity; it contains a peptide sequence homologous with the β1-domain region of a MHC class II antigen from CD4.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18958225
| Purity |
≥98% |
|---|---|
| Formula |
C22H33N7O8 |
| Formula Wt. |
523.5 |
Iwao Y, Fujimura T. Activation of Xenopus eggs by RGD-containing peptides accompanied by intracellular Ca2+ release. Dev Biol. 1996 Aug 1;177(2):558-67. PMID: 8806831.
Mazerolles F, Durandy A, Piatier-Tonneau D, et al. Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens. Cell. 1988 Nov 4;55(3):497-504. PMID: 3263212.
Auffray C, Novotny J. Speculations on sequence homologies between the fibronectin cell-attachment site, major histocompatibility antigens, and a putative AIDS virus polypeptide. Hum Immunol. 1986 Apr;15(4):381-90. PMID: 3009364.
