Share this post on:

Puupehenone

Puupehenone is a sesquiterpene found in marine sponges that displays some antioxidative and antiangiogenic activities. In separate cellular models, puupehenone inhibits cell growth and also decreases radical generation by DPPH.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18955635

Cas No.

73573-17-8

Purity

≥94%

Formula

C21H28O3

Formula Wt.

328.45

IUPAC Name

10-hydroxy-4,4,6a,12b-tetramethyl-2,3,4a,5,6,12a-hexahydro-1H-benzo[a]xanthen-9-one

Solubility

0.1 mg/mL ethanol, 0.3 mg/mL methanol*protect from light*pack under inert gas

Appearance

Brown powder

Castro ME, González-Iriarte M, Barrero AF, et al. Study of puupehenone and related compounds as inhibitors of angiogenesis. Int J Cancer. 2004 May 20;110(1):31-8. PMID: 15054866.

Takamatsu S, Hodges TW, Rajbhandari I, et al. Marine natural products as novel antioxidant prototypes. J Nat Prod. 2003 May;66(5):605-8. PMID: 12762791.

BAL-4816