Pseudoprotodioscin
Pseudoprotodioscin is a steroidal saponin originally found in species of Tribulus, Trigonella, and Smilax. Pseudoprotodioscin exhibits anti-inflammatory and anticancer activities. This compound inhibits melanogenesis in melanoma cells and inhibits production of inflammatory cytokines such as TNF-α in THP-1 cells. Pseudoprotodioscin displays mild cytotoxicity across several cancer cell lines.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18955434
| Cas No. |
102115-79-7 |
|---|---|
| Purity |
≥98% |
| Formula |
C51H82O21 |
| Formula Wt. |
1031.18 |
| IUPAC Name |
(3β,25R)-26-(β-D-Glucopyranosyloxy)furosta-5,20(22)-dien-3-yl 6-deoxy-α-L-mannopyranosyl-(1->;2)-[6-deoxy-α-L-mannopyranosyl-(1->;4)]-β-D-glucopyranoside |
| Appearance |
White to off white powder |
Kawabata T, Cui MY, Hasegawa T, et al. Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds. Planta Med. 2011 May;77(7):705-10. PMID: 20979021.
Dinchev D, Janda B, Evstatieva L, et al. Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Phytochemistry. 2008 Jan;69(1):176-86. PMID: 17719068.
Dong M, Feng XZ, Wu LJ, et al. Two new steroidal saponins from the rhizomes of Dioscorea panthaica and their cytotoxic activity. Planta Med. 2001 Dec;67(9):853-7. PMID: 11745024.
