Palmitoyl-L-carnitine
Palmitoyl-L-carnitine is a long chain acylcarnitine that is involved in fatty acid metabolism. This compound is a substrate used to stimulate mitochondrial respiration and to study mitochondrial function in research models. Palmitoyl-L-carnitine may stimulate sphingosine-1-phosphate (S1P) receptors.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18952548
| Cas No. |
18877-64-0 |
|---|---|
| Purity |
≥98% |
| Formula |
C23H46NO4 Cl |
| Formula Wt. |
436.1 |
| IUPAC Name |
[(2R)-3-carboxy-2-hexadecanoyloxypropyl]-trimethylazanium;chloride |
| Synonym |
O-Palmitoyl-L-carnitine chloride |
| Solubility |
Soluble in water with heat or sonication. |
| Appearance |
White Powder |
Monternier PA, Marmillot V, Rouanet JL, et al. Mitochondrial phenotypic flexibility enhances energy savings during winter fast in king penguin chicks. J Exp Biol. 2014 Aug 1;217(Pt 15):2691-7. PMID: 24803465.
Bernatoniene J, Majiene D, Peciura R, et al. The effect of Ginkgo biloba extract on mitochondrial oxidative phosphorylation in the normal and ischemic rat heart. Phytother Res. 2011 Jul;25(7):1054-60. PMID: 21259351.
Muraki K, Imaizumi Y. A novel action of palmitoyl-L-carnitine in human vascular endothelial cells. J Pharmacol Sci. 2003 Jul;92(3):252-8. PMID: 12890891.
