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Nidulal

Nidulal is a sesquiterpene found in the basidiomycete Nidula candida. Nidulal exhibits antibiotic and cytotoxic activities. Nidulal induces differentiation of promyelocytic leukemia cells and activates expression of alkaline phosphatase in vitro.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18948708

Purity

≥95%

Formula

C15H16O5

Formula Wt.

276.28

IUPAC Name

4-(3-methyl-2,9-dioxo-1,6-dioxaspiro[4.4]nona-3,7-dien-8-yl)cyclohexane-1-carbaldehyde

Solubility

Soluble in ethanol, methanol or DMSO.

Erkel G, Becker U, Anke T, et al. Nidulal, a novel inducer of differentiation of human promyelocytic leukemia cells from Nidula candida. J Antibiot (Tokyo). 1996 Dec;49(12):1189-95. PMID: 9031663.

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