N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys
F-peptide binds n-formyl peptide receptors (FPRs) on neutrophils, playing a role in neutrophil activation.
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18946782
Cas No. |
71901-21-8 |
---|---|
Purity |
≥95% |
Formula |
C43H65O7N9 |
Formula Wt. |
824.04 |
IUPAC Name |
6-amino-2-[[2-[2-[[2-[[2-(2-formamidohexanoylamino)-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]hexanoylamino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoic acid |
Synonym |
F-Chemotactic peptide, F-Peptide; N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys |
Appearance |
White to off white powder |
Allen RA, Erickson RW, Jesaitis AJ. Identification of a human neutrophil protein of Mr 24 000 that binds N-formyl peptides: co-sedimentation with specific granules. Biochim Biophys Acta. 1989 Apr 25;991(1):123-33. PMID: 2653446.