Myclobutanil
Myclobutanil is an antifungal compound that suppresses ergosterol and fungal cell wall synthesis by inhibiting sterol 14α demethylase. Myclobutanil also weakly inhibits testosterone production in mammals.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18946003
| Cas No. |
88671-89-0 |
|---|---|
| Purity |
≥97% |
| Formula |
C15H17ClN4 |
| Formula Wt. |
288.78 |
| Chemical Name |
α-Butyl-α-(4-chlorophenyl)-1H-1,2,4-triazole-1- propanenitrile |
| IUPAC Name |
2-(4-chlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)hexanenitrile |
| Synonym |
Nova; Rally; Systhane |
| Melting Point |
63-68°C |
| Solubility |
Soluble in water and aromatic hydrocarbons. Insoluble in aliphatic hydrocarbons. |
| Appearance |
White to off white powder |
Goetz AK, Rockett JC, Ren H, et al. Inhibition of rat and human steroidogenesis by triazole antifungals. Syst Biol Reprod Med. 2009 Dec;55(5-6):214-26. PMID: 19938956.
Schnabel G, Jones AL. The 14alpha-Demethylasse(CYP51A1) Gene is Overexpressed in Venturia inaequalis Strains Resistant to Myclobutanil. Phytopathology. 2001 Jan;91(1):102-10. PMID: 18944284.
