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Meglumine

Meglumine is an amino sugar derived from sorbitol that is clinically used as a bulking agent for other active compounds in the formulation of various pharmaceutical drugs, such as meglumine antimoniate and flunixin meglumine.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18942952

Cas No.

6284-40-8

Purity

≥98%

Formula

C7H17NO5

Formula Wt.

195.21

Chemical Name

1-Deoxy-1-(methylamino)-D-glucitol

IUPAC Name

(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol

Synonym

N-Methylglucamine; Meglumine

Melting Point

128-129°C

Solubility

Soluble in water and alcohol.

Appearance

White to off white powder

Borborema SE, Schwendener RA, Osso JA Jr, et al. Uptake and antileishmanial activity of meglumine antimoniate-containing liposomes in Leishmania (Leishmania) major-infected macrophages. Int J Antimicrob Agents. 2011 Oct;38(4):341-7. PMID: 21783345.

Rossetti RC, Perdigão A, Mesquita FS, et al. Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows. Theriogenology. 2011 Sep 1;76(4):751-8. PMID: 21719091.

(-)-Blebbistatin