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[Lys8]-Vasopressin

Vasopressin is a peptide that acts on vasopressin receptors, modulating intestinal motility, inducing vasoconstriction in arteries, and inducing contraction of various muscles. Vasopressin also exhibits antidiuretic activity, occasionally resulting in hyponatremia in vivo and in clinical settings.

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/18830418

Purity

≥95%

Formula

C46H65N13O12S2

Formula Wt.

1056.24

IUPAC Name

(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide


product targets : Pyk2 inhibitors

Chelko SP, Schmiedt CW, Lewis TH, et al. Vasopressin-induced constriction of the isolated rat occipital artery is segment dependent. J Vasc Res. 2013;50(6):478-85. PMID: 24192548.

Mastropaolo M, Zizzo MG, Auteri M, et al. Arginine vasopressin, via activation of post-junctional V1 receptors, induces contractile effects in mouse distal colon. Regul Pept. 2013 Nov 10;187:29-34. PMID: 24185041.

Salazar M, Hu BB, Vazquez J, et al. Exogenous Vasopressin-Induced Hyponatremia in Patients With Vasodilatory Shock: Two Case Reports and Literature Review. J Intensive Care Med. 2013 Oct 7. [Epub ahead of print]. PMID: 24106070.

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