Lupinine
Lupinine is a plant alkaloid found in species of Loranthus, Calia, and Lupinus. Lupinine exhibits immunostimulatory activity, potentially through the activation of CD69. Lupinine inhibits cholinesterases and may also inhibit heparin.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18940896
| Cas No. |
486-70-4 |
|---|---|
| Purity |
≥98% |
| Formula |
C10H19NO |
| Formula Wt. |
169.26 |
| Chemical Name |
[1R-trans]-Octahydro-2H-quinolizine-1-methanol |
| IUPAC Name |
[(1R,9aR)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizin-1-yl]methanol |
| Synonym |
l-Lupine; (-)-Lupinine |
| Melting Point |
68.5-69.2°C |
| Solubility |
Soluble in water, alcohol, chloroform and ether. |
| Appearance |
Light brown orange crystalline powder |
Basova NE, Kormilitsyn BN, Perchenok AIu, et al. Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal. Zh Evol Biokhim Fiziol. 2012 May-Jun;48(3):213-8. PMID: 22827020.
Omeje EO, Osadebe PO, Nworu CS, et al. A novel sesquiterpene acid and an alkaloid from leaves of the Eastern Nigeria mistletoe, Loranthus micranthus with potent immunostimulatory activity on C57BL6 mice splenocytes and CD69 molecule. Pharm Biol. 2011 Dec;49(12):1271-6. PMID: 21988279.
Usmanova DM, Musaev UN, Efimov VS. Antiheparin activity of polymers based on the alkaloid, lupinine. Farmakol Toksikol. 1979 Nov-Dec;42(6):628-32. PMID: 499471.
