L-Phenylalaninol
L-Phenylalaninol is a non-essential amino acid that exhibits anticancer and antacid activities. In melanoma cells, L-phenylalaninol increases activity of cytochrome c reductase and tau-glutamyl transpeptidase, inhibiting cell proliferation. L-Phenylalaninol also inhibits intestinal absorption of phenylalanine and may decrease gastric acid secretion and ulcer formation.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18936906
| Cas No. |
3182-95-4 |
|---|---|
| Purity |
≥98% |
| Formula |
C9H13NO |
| Formula Wt. |
151.21 |
| Chemical Name |
(S)-2-Amino-3-phenyl-1-propanol |
| IUPAC Name |
(2S)-2-amino-3-phenylpropan-1-ol |
| Synonym |
S-Phenylalaninol; β-amino-(S)-(9CI)Benzenepropanol |
| Melting Point |
90-93°C |
| Solubility |
Soluble in water and methanol. |
| Appearance |
Gray or slightly yellow powder |
Landau O, Wasserman L, Deutsch AA, et al.Amino acid alcohols: growth inhibition and induction of differentiated features in melanoma cells. Cancer Lett. 1993 May 14;69(3):203-8. PMID: 8099846.
Hashizume H, Miyamae T, Morikawa T, et al. Effects of phenylalaninol on centrally induced gastric acid secretion. Chem Pharm Bull (Tokyo). 1992 Nov;40(11):3113-4. PMID: 1477931.
Shimomura K, Fukushima T, Danno T, et al. Inhibition of intestinal absorption of phenylalanine by phenylalaninol. J Biochem. 1975 Aug;78(2):269-75. PMID: 1228171.
