Erythropoietin
Erythropoietin is an endogenous glycoprotein hormone that is involved in the production of red blood cells; it binds the erythropoietin receptor (EpoR) and is clinically used to treat anemia. Erythropoietin exhibits pro-angiogenic, neuroprotective, cognition enhancing, and antidepressant activities. Erythropoietin decreases hepcidin levels and increases absorption of iron. In vitro, this compound stimulates angiogenesis and increases proliferation of smooth muscle fibers. When administered clinically, erythropoietin improves memory and mood.
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/18922233
| Cas No. |
11096-26-7 |
|---|---|
| Purity |
≥97% |
| Synonym |
Erythropoiesis stimulating factor; Hemopoietine; ESF; Epo |
| Solubility |
Soluble in water. |
| Appearance |
White powder |
Liu S, Ren J, Hong Z, et al. Efficacy of erythropoietin combined with enteral nutrition for the treatment of anemia in Crohns disease: a prospective cohort study. Nutr Clin Pract. 2013 Feb;28(1):120-7. PMID: 23064018.
Ashby DR, Gale DP, Busbridge M, et al. Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin. Haematologica. 2010 Mar;95(3):505-8. PMID: 19833632.
Miskowiak K, Inkster B, Selvaraj S, et al. Erythropoietin improves mood and modulates the cognitive and neural processing of emotion 3 days post administration. Neuropsychopharmacology. 2008 Feb;33(3):611-8. PMID: 17473836.
